Side effects or not, antidepressants were the most commonly prescribed medications in the United States in 2007. the use of antidepressants has increased in direct to consumer advertising, the people will lead to anti-depressants at the request of doctors. Is there any problem if antidepressants are prescribed, but many doctors believe it is better to write about how under-prescribe because depression can lead to suicide.
What they do
Antidepressantsare based on the theory that due to low levels of the brain neurotransmitter serotonin and noradrenaline depression. It is likely that work by increasing levels of these neurotransmitters. Since antidepressants can stabilize the emotions, are also planned for panic disorders, chronic pain, mood disorders, eating disorders and obsessive-compulsive disorder.
Common antidepressants
(1) selective serotonin reuptake inhibitors are believed (SSRIs) increase serotonin levels forBrain. Common SSRIs are Prozac, Paxil and Zoloft. Side effects may be sexual dysfunction, nausea, loss of appetite, restlessness and insomnia.
(2) serotonin reuptake inhibitor, norepinephrine (SNRIs) such as Effexor and Cymbalta Pristig increases both serotonin and norepinephrine. Side effects include those of SSRIs together with vivid dreams.
(3) noradrenaline reuptake inhibitors and dopamine (NDRIs) increased levels of norepinephrine and dopamine. The side effects of agitation and bloodPressure was detected. This drug is marketed under the trade name Wellbutrin (for depression) and Zyban (for smoking).
(4), noradrenaline and specific serotonergic antidepressants (NASSAs) as TOLVON and Remeron are newer drugs that increase serotonin and norepinephrine, but it can not (although different) side effects, such as fatigue, increased appetite and increased weight.
(5), norepinephrine reuptake inhibitors (NRI), as increased noradrenaline Edronaxonly and are meant to improve concentration and motivation.
(6) antidepressants combined with the effects of neurotransmitters such as Desyrel (trazodone brand name) can be useful for panic disorder, anxiety and restlessness. But Remeron birth defects may, premature births and miscarriages, and Serzone may worsen pre-existing liver disease.
Other considerations
A new theory suggests that reduced sexual arousal and pleasure produced by increased levels of serotonin inSSRIs can inhibit the processes of love, the bond with a mate and develop feelings of love and affection in general.
Some antidepressants may increase suicidal thoughts and behaviors in those of 25, and Paxil may increase hostility and aggression. Although antidepressants can alleviate depression, can not do anything for mania, and even trigger manic episodes in bipolar patients.
Why suppress rapid eye movement (REM) sleep, nightmares may develop when intenseAntidepressants are stopped. SSRI's and SNRI withdrawal symptoms can be particularly serious, if not done gradually.
Antidepressants work?
Regardless of the phenomenal sales success, there is little evidence that antidepressants actually work. Of all the studies submitted to the FDA in 1987-2004 showed only half of any significant effect of antidepressants to placebos, while up to half of patients treated with antidepressants showed no improvementWhatever.
In February 2008 a study on the most commonly prescribed antidepressants has been in the Public Library of Science Medicine, an online magazine, published by Professor Irving Kirsch University of Hull in Britain. Patients taking antidepressants showed only an improvement in "very little" of 2 points on the Hamilton Depression Scale compared with those treated with placebo.
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